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Pathologic evidence of arrhythmogenic cardiomyopathy and myocarditis in two siblings.
d'Amati, G; Fiore, F; Giordano, C; De Biase, L; Laurenti, A; Gallo, P.
Affiliation
  • d'Amati G; Department of Experimental Medicine, L'Aquila University, Rome, Italy.
  • Fiore F; Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
  • Giordano C; Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
  • De Biase L; Institute of Cardiac Surgery, La Sapienza University, Rome, Italy.
  • Laurenti A; Institute of Cardiac Surgery, La Sapienza University, Rome, Italy.
  • Gallo P; Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy.
Cardiovasc Pathol ; 7(1): 39-46, 1998.
Article in En | MEDLINE | ID: mdl-25989962
This report describes the case of two siblings who underwent heart transplantation with a clinical diagnosis of mildly dilated cardiomyopathy. Pathological examination of the hearts revealed arrhythmogenic (right ventricular) cardiomyopathy, adipose type, associated with biventricular myocarditis in both the recipients' hearts. Family history revealed the occurrence of dilated cardiomyopathy and myocarditis in their father and his sister. To our knowledge, this is the first pathological demonstration of arrhythmogenic cardiomyopathy and myocarditis in siblings. We think this report substantiates a genetic ground for the relationship between these two heart conditions.

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cardiovasc Pathol Journal subject: ANGIOLOGIA / CARDIOLOGIA / PATOLOGIA Year: 1998 Document type: Article Affiliation country: Country of publication:

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Cardiovasc Pathol Journal subject: ANGIOLOGIA / CARDIOLOGIA / PATOLOGIA Year: 1998 Document type: Article Affiliation country: Country of publication: